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May 5, 2007 comparison of viagra, levitra & cialis for sexual dysfunction: effectiveness, onset of action, duration of effect, side effects.Viagra, cialis, levitra, and stendra are oral medications for treating erectile dysfunction. All four work in similar ways, but there are also key differences, such as how long they work and their side.Sildenafil, viagra, and levitra (vardenafil) have relatively rapid onsets of action compared to cialis (tadalafil). Sildenafil, viagra, and levitra can be effective in as little as 1 hour, while cialis.– taking viagra on a full stomach will slow the effects of the drug. If taken on a full stomach, viagra will take effect in about 12 hours. Levitra: – takes about 30 minutes to an hour to take effect –.

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